Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 10/20 | 0.51 |
| ▸ | CTPS2 | Q9NRF8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077153 | 0.93 | CTPS1 (0.46) | CTPS1CTPS2ABL1 | |
| SCHEMBL21076934 | 0.88 | CTPS1 (0.45) | CTPS1CTPS2 | |
| SCHEMBL21077093 | 0.86 | CTPS1 (0.55) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077203 | 0.84 | CTPS1 (0.51) | CTPS1CTPS2ABL1 | |
| SCHEMBL21076932 | 0.84 | CTPS1 (0.52) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077178 | 0.84 | CTPS1 (0.44) | CTPS1CTPS2 | |
| SCHEMBL21044219 | 0.83 | CTPS1 (0.72) | CTPS1CTPS2 | |
| SCHEMBL30528948 | 0.83 | CTPS1 (0.72) | CTPS1CTPS2 | |
| SCHEMBL21077165 | 0.83 | CTPS1 (0.47) | CTPS1CTPS2 | |
| SCHEMBL21077050 | 0.83 | CTPS1 (0.51) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |