Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 7/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CDC25C | P30307 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076863 | 0.86 | ADRB3 (0.39) | CTPS1ADRB3MEN1KMT2ANPC1 | |
| SCHEMBL21044160 | 0.82 | CTPS1 (0.58) | CTPS1 | |
| SCHEMBL21077018 | 0.79 | CTPS1 (0.53) | CTPS1ADRB3MEN1KMT2AWNT3A | |
| SCHEMBL21077047 | 0.79 | CTPS1 (0.52) | CTPS1ADRB3MEN1KMT2AWNT3A | |
| SCHEMBL21077234 | 0.76 | CTPS1 (0.40) | CTPS1MEN1KMT2ALMNANPC1 | |
| SCHEMBL21077175 | 0.76 | CTPS1 (0.44) | CTPS1MEN1KMT2AWNT3ANPC1 | |
| SCHEMBL21077147 | 0.75 | CTPS1 (0.54) | CTPS1ADRB3MEN1KMT2ANPC1 | |
| SCHEMBL21077060 | 0.75 | CTPS1 (0.56) | CTPS1 | |
| SCHEMBL21077117 | 0.75 | CTPS1 (0.55) | CTPS1ADRB3 | |
| SCHEMBL21077199 | 0.75 | CTPS1 (0.53) | CTPS1ADRB3MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |