Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 10/20 | 0.55 |
| ▸ | CTPS2 | Q9NRF8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077134 | 0.86 | CTPS1 (0.58) | CTPS1CTPS2MEN1KMT2ARAB9A | |
| SCHEMBL21077207 | 0.85 | CTPS1 (0.69) | CTPS1CTPS2 | |
| SCHEMBL21044286 | 0.83 | CTPS1 (0.79) | CTPS1CTPS2 | |
| SCHEMBL21077093 | 0.82 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21077065 | 0.82 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21077135 | 0.81 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21077245 | 0.81 | CTPS1 (0.58) | CTPS1CTPS2RAB9A | |
| SCHEMBL21077114 | 0.81 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21077008 | 0.80 | CTPS1 (0.51) | CTPS1CTPS2 | |
| SCHEMBL21077003 | 0.80 | CTPS1 (0.56) | CTPS1CTPS2RAB9ANTMT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |