Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077245 | 0.86 | CTPS1 (0.58) | CTPS1IRAK4NPC1RAB9AABCB1 | |
| SCHEMBL21076999 | 0.86 | CTPS1 (0.68) | CTPS1 | |
| SCHEMBL21076877 | 0.84 | CTPS1 (0.57) | CTPS1HTTMAPTALDH1A1 | |
| SCHEMBL31152569 | 0.83 | CTPS1 (0.74) | CTPS1 | |
| SCHEMBL21044413 | 0.83 | CTPS1 (0.74) | CTPS1 | |
| SCHEMBL21076890 | 0.79 | CTPS1 (0.57) | CTPS1IRAK4ABCB1ABCC1 | |
| SCHEMBL21077007 | 0.79 | L3MBTL1 (0.51) | CTPS1GAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL21077075 | 0.76 | CTPS1 (0.64) | CTPS1GAASMN1; SMN2HTTMAPT | |
| SCHEMBL21077128 | 0.76 | CTPS1 (0.67) | CTPS1KDM4EKMT2AMEN1 | |
| SCHEMBL21077246 | 0.76 | CTPS1 (0.54) | CTPS1GAASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |