Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15522136 | 0.89 | DGAT1 (0.41) | DGAT1KCNH2CA12CA1CA2 | |
| SCHEMBL15742157 | 0.88 | DGAT1 (0.42) | DGAT1KCNH2CA12CA1CA2 | |
| SCHEMBL15733091 | 0.83 | DGAT1 (0.53) | DGAT1KCNH2 | |
| SCHEMBL15521971 | 0.80 | DGAT1 (0.39) | DGAT1KCNH2 | |
| SCHEMBL15743018 | 0.76 | DGAT1 (0.32) | DGAT1KCNH2 | |
| SCHEMBL15733007 | 0.74 | DGAT1 (0.42) | DGAT1KCNH2 | |
| SCHEMBL14062292 | 0.74 | PTK2 (0.36) | DGAT1 | |
| SCHEMBL15745364 | 0.73 | KDM4E (0.38) | DGAT1 | |
| SCHEMBL17250107 | 0.73 | KCNH2 (0.37) | DGAT1KCNH2 | |
| SCHEMBL15733050 | 0.72 | DGAT1 (0.54) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492474-A1 | INTERMEDIATES USED IN THE PRODUCTION OF DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GlaxoSmithKline LLC (US) | 2019-06-05 | — | — | EP | disclosed |