Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 3/20 | 0.42 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20820953 | 0.92 | KMT2A (0.46) | KMT2ASLC6A2SLC6A3TDP1TACR2 | |
| SCHEMBL27324965 | 0.88 | KMT2A (0.45) | KMT2ASLC6A2SLC6A3TDP1TACR2 | |
| SCHEMBL13857157 | 0.88 | NT5E (0.46) | KMT2ASLC6A2SLC6A3TDP1TACR2 | |
| SCHEMBL21077811 | 0.84 | KMT2A (0.49) | KMT2ASLC6A2SLC6A3TDP1TACR2 | |
| SCHEMBL5689323 | 0.84 | GJB2 (0.48) | SLC6A2TACR2NT5EGJB2BCHE | |
| SCHEMBL5689122 | 0.84 | GJB2 (0.48) | SLC6A2TACR2NT5EGJB2BCHE | |
| SCHEMBL5688893 | 0.84 | GJB2 (0.48) | SLC6A2TACR2NT5EGJB2BCHE | |
| SCHEMBL24107976 | 0.84 | LGALS9 (0.56) | SLC6A2TACR2LGALS9LGALS1LGALS3 | |
| SCHEMBL18942034 | 0.83 | NT5E (0.47) | KMT2ASLC6A2SLC6A3TDP1LGALS9 | |
| SCHEMBL20759687 | 0.82 | SLC6A2 (0.45) | SLC6A2TACR2LGALS9LGALS1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492482-A1 | VACCINE AGAINST KLEBSIELLA PNEUMONIAE | Vaxxilon AG (CH) | 2019-06-05 | — | — | EP | disclosed |