Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187629 | 0.84 | SLC18A3 (0.56) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL5187550 | 0.78 | ALDH1A1 (0.57) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL6988277 | 0.78 | ALDH1A1 (0.57) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL2993708 | 0.77 | SRD5A2 (0.57) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL13874024 | 0.74 | MEN1 (0.66) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL11758964 | 0.74 | LMNA (0.39) | ALDH1A1KMT2APOLBMEN1PKM | |
| Hydrochloric Acid SCHEMBL3846012 | 0.73 | MEN1 (0.69) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL4771785 | 0.71 | SLC18A3 (0.56) | SLC18A3ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL13906351 | 0.68 | ESR2 (0.42) | ALDH1A1KMT2AMEN1MAPK1LMNA | |
| SCHEMBL13906347 | 0.68 | ESR2 (0.42) | ALDH1A1KMT2AMEN1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |