Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12587298 | 0.78 | CA1 (0.54) | TDP1TSHRCA1 | |
| SCHEMBL17211862 | 0.76 | ALDH1A1 (0.45) | TDP1TSHRCA1 | |
| SCHEMBL15759387 | 0.76 | TDP1 (0.44) | TDP1TSHRCA1 | |
| SCHEMBL20029568 | 0.75 | — | — | |
| SCHEMBL18124258 | 0.74 | TDP1 (0.36) | TDP1TSHRCA1 | |
| SCHEMBL29170705 | 0.74 | — | — | |
| SCHEMBL25393835 | 0.74 | — | — | |
| SCHEMBL8058354 | 0.74 | — | — | |
| SCHEMBL13469005 | 0.73 | THRB (0.39) | — | |
| SCHEMBL29869300 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |