Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742135 | 0.90 | NAMPT (0.66) | NAMPTL3MBTL3L3MBTL1SIGMAR1GABRD | |
| SCHEMBL7170178 | 0.87 | NAMPT (0.67) | NAMPTL3MBTL3L3MBTL1SIGMAR1HSD17B10 | |
| SCHEMBL1914320 | 0.87 | NAMPT (0.60) | NAMPTL3MBTL3L3MBTL1SIGMAR1 | |
| SCHEMBL6631346 | 0.86 | L3MBTL3 (0.64) | NAMPTL3MBTL3L3MBTL1SIGMAR1GABRD | |
| SCHEMBL17888390 | 0.85 | GABRD (0.68) | NAMPTL3MBTL3L3MBTL1GABRDGABRA1 | |
| SCHEMBL7170182 | 0.83 | NAMPT (0.65) | NAMPTSIGMAR1GABRDGABRA1GABRB1 | |
| SCHEMBL21078284 | 0.81 | L3MBTL3 (0.58) | NAMPTL3MBTL3L3MBTL1GABRDGABRA1 | |
| SCHEMBL17886813 | 0.81 | HPGD (0.58) | NAMPTL3MBTL3L3MBTL1GABRDGABRA1 | |
| SCHEMBL6631344 | 0.81 | HSD17B10 (0.67) | NAMPTL3MBTL3L3MBTL1SIGMAR1HSD17B10 | |
| SCHEMBL6634031 | 0.81 | NAMPT (0.66) | NAMPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |