Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014326 | 0.83 | ALDH1A1 (0.30) | — | |
| Propionic Acid SCHEMBL27531858 | 0.82 | FFAR3 (0.48) | KDM2BDPP4 | |
| SCHEMBL10437854 | 0.81 | NLRP3 (0.36) | — | |
| SCHEMBL256670 | 0.81 | — | — | |
| SCHEMBL17888406 | 0.77 | KDM2B (0.33) | KDM2B | |
| SCHEMBL10523843 | 0.77 | KDM2B (0.33) | KDM2B | |
| SCHEMBL15733203 | 0.77 | KDM2B (0.33) | KDM2B | |
| SCHEMBL2587904 | 0.76 | MAPT (0.47) | — | |
| SCHEMBL2583107 | 0.76 | MAPT (0.47) | — | |
| SCHEMBL2583112 | 0.76 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |