Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 8/20 | 0.53 |
| ▸ | PYGL | P06737 | 7/20 | 0.53 |
| ▸ | PYGM | P11217 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109016 | 0.93 | PYGL (0.53) | CYP51A1PYGLPYGMAVPR1AOXTR | |
| SCHEMBL2606797 | 0.93 | PYGL (0.53) | CYP51A1PYGLPYGMAVPR1AOXTR | |
| SCHEMBL2606950 | 0.91 | PYGL (0.52) | CYP51A1PYGLPYGMALDH1A1AVPR1A | |
| SCHEMBL2606947 | 0.91 | PYGL (0.52) | CYP51A1PYGLPYGMALDH1A1AVPR1A | |
| SCHEMBL2606894 | 0.90 | PYGL (0.51) | CYP51A1PYGLPYGMALDH1A1AVPR1A | |
| SCHEMBL2606896 | 0.90 | PYGL (0.51) | CYP51A1PYGLPYGMAVPR1AOXTR | |
| SCHEMBL2608587 | 0.89 | CYP51A1 (0.51) | CYP51A1PYGLPYGMRAB9AALDH1A1 | |
| SCHEMBL2607006 | 0.89 | PYGL (0.50) | CYP51A1PYGLPYGMAVPR1AOXTR | |
| SCHEMBL2607191 | 0.88 | CYP51A1 (0.51) | CYP51A1PYGLPYGMRAB9AALDH1A1 | |
| SCHEMBL2108267 | 0.87 | CYP51A1 (0.62) | CYP51A1PYGLPYGMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |