Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 8/20 | 0.53 |
| ▸ | CYP51A1 | Q16850 | 6/20 | 0.53 |
| ▸ | PYGM | P11217 | 1/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606797 | 1.00 | PYGL (0.53) | PYGLCYP51A1PYGMAVPR1AOXTR | |
| SCHEMBL2606947 | 0.96 | PYGL (0.52) | PYGLCYP51A1PYGMAVPR1AALB | |
| SCHEMBL2606950 | 0.96 | PYGL (0.52) | PYGLCYP51A1PYGMAVPR1AALB | |
| SCHEMBL2606894 | 0.96 | PYGL (0.51) | PYGLCYP51A1PYGMAVPR1AALB | |
| SCHEMBL2606896 | 0.96 | PYGL (0.51) | PYGLCYP51A1PYGMAVPR1AOXTR | |
| SCHEMBL2607006 | 0.94 | PYGL (0.50) | PYGLCYP51A1PYGMAVPR1AOXTR | |
| SCHEMBL2107845 | 0.93 | CYP51A1 (0.53) | PYGLCYP51A1PYGMAVPR1AOXTR | |
| SCHEMBL2606951 | 0.91 | PYGL (0.55) | PYGLCYP51A1 | |
| SCHEMBL2606954 | 0.88 | PYGL (0.51) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2606897 | 0.88 | PYGL (0.51) | PYGLCYP51A1PYGMALBIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |