Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 12/20 | 0.56 |
| ▸ | CDK1 | P06493 | 12/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 12/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078511 | 0.85 | CCNB2 (0.46) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL21078636 | 0.82 | CCNB2 (0.50) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL21011224 | 0.81 | CDK1 (0.60) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL19864855 | 0.76 | CDK1 (0.60) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL26354839 | 0.76 | CDK1 (0.72) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL2718523 | 0.75 | CDK1 (0.59) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL29767914 | 0.74 | ADORA2A (0.48) | CCNB2CDK1CCNB1CCNB3ADORA2A | |
| SCHEMBL18521194 | 0.73 | CCNB2 (0.82) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL26199920 | 0.73 | CDK1 (0.57) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL24946009 | 0.72 | CDK1 (0.59) | CCNB2CDK1CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169221-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Biopharma, Inc. | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169221-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | CCNB2 3862/4885CDK1 2755/4885CCNB1 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.