Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271315 | 0.85 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL5884350 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL16960402 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL16595240 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1LMNASMN1; SMN2MAPK1TDP1 | |
| SCHEMBL21710001 | 0.79 | ACHE (0.38) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL4311186 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL19461719 | 0.78 | MCHR1 (0.40) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL131996 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL16960908 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL1330449 | 0.77 | SLC6A4 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492465-B1 | S1P1 AGONIST AND APPLICATION THEREOF | SHIJIAZHUANG SAGACITY NEW DRUG DEV CO LTD (CN) | 2021-03-24 | — | — | EP | disclosed |
| EP-3492465-A1 | S1P1 AGONIST AND APPLICATION THEREOF | Shijiazhuang Sagacity New Drug Development Co., Ltd. (CN) | 2019-06-05 | — | — | EP | disclosed |