SCHEMBL2107969

SCHEMBL2107969

CCC(CCN)NC(C)O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.33
TSHR P16473 1/20 0.33
GABBR2 O75899 2/20 0.32
GABBR1 Q9UBS5 2/20 0.32
SPHK1 Q9NYA1 1/20 0.30
LMNA P02545 2/20 0.30
CNR1 P21554 1/20 0.30
ADRA1A P35348 1/20 0.30
TRPV1 Q8NER1 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TRPA1 O75762 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2058301 0.81 TSHR (0.36) TSHRLMNACNR1ADRA1ATDP1
SCHEMBL20632266 0.81 TSHR (0.36) TSHRLMNACNR1ADRA1ATDP1
SCHEMBL4483062 0.81
SCHEMBL1199681 0.80
SCHEMBL7563548 0.77 ALDH1A1 (0.38) TSHRSPHK1TDP1
SCHEMBL20613038 0.76 GABBR2 (0.31) GABBR2GABBR1
SCHEMBL6805820 0.76 SPHK1 (0.42) SPHK1LMNAKDM4E
SCHEMBL11801890 0.74 SPHK1 (0.45) SPHK1LMNAKDM4E
SCHEMBL11798137 0.74 SPHK1 (0.45) SPHK1LMNAKDM4E
SCHEMBL118939 0.74 SPHK1 (0.45) SPHK1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178828-B1 ALDIMINES AND COMPOUNDS CONTAINING ALDIMINE SIKA TECH AG (CH) 2019-06-26 EP disclosed
EP-2651875-B1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-30 EP disclosed
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP disclosed
EP-2132248-B1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2016-07-13 EP disclosed
US-20150368509-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2015-12-24 US disclosed
EP-2651875-A1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP disclosed
EP-2651876-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP disclosed
US-20130261270-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-10-03 US disclosed
US-8519038-B2 Aldimines and compositions comprising aldimine SIKA TECHNOLOGY AG (CH) 2013-08-27 US disclosed
US-8455100-B2 Aldimines comprising hydroxyl groups, and compositions containing aldimine SIKA TECHNOLOGY AG (CH) 2013-06-04 US disclosed
EP-2072550-A1 Hardening compounds with reduced gas emission Sika Technology AG (CH) 2009-06-24 EP disclosed
WO-2009027511-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP disclosed
WO-2009010522-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE SIKA TECHNOLOGY AG (CH) 2009-01-22 WO disclosed
EP-2017260-A1 Aldimines and compounds containing aldimine Sika Technology AG (CH) 2009-01-21 EP disclosed
WO-2008116928-A1 ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN SIKA TECHNOLOGY AG (CH) 2008-10-02 WO disclosed
EP-1975190-A1 Aldimines with reactive groups containing active hydrogen Sika Technology AG (CH) 2008-10-01 EP disclosed
EP-1934169-A1 ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF Sika Technology AG (CH) 2008-06-25 EP disclosed
EP-1772447-A1 Aldimines with reactive groups comprising active hydrogen, and their use Sika Technology AG (CH) 2007-04-11 EP disclosed
WO-2007036571-A1 ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF SIKA TECHNOLOGY AG (CH) 2007-04-05 WO disclosed