SCHEMBL2108014

SCHEMBL2108014

CC=C(C(=O)O)c1ccccc1Oc1cc(C(C)(C)C)ccn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.36
SRC P12931 1/20 0.35
TGFBR1 P36897 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
CYP2C19 P33261 1/20 0.34
MAPK8 P45983 2/20 0.34
MAPK10 P53779 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MAPT P10636 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
HTT P42858 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
P2RY1 P47900 2/20 0.32
P2RY14 Q15391 1/20 0.32
CTNNB1 P35222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853904 1.00 PKM (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2853900 0.90 SRC (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2108009 0.90 SRC (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2108015 0.90 SRC (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL203540 0.83 PKM (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2847819 0.82 MAPK8 (0.45) SRCTGFBR1KMT2AMEN1MAPK8
SCHEMBL29393804 0.82 MEN1 (0.37) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL203539 0.82 MEN1 (0.37) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL203541 0.81 SRC (0.38) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL18281651 0.80 HCRTR1 (0.39) SRCTGFBR1MAPK8MAPK10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed