SCHEMBL203540

SCHEMBL203540

CC(C)=C(C(=O)O)c1ccccc1Oc1cc(C(C)(C)C)ccn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.36
SRC P12931 1/20 0.35
TGFBR1 P36897 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
MAPK8 P45983 2/20 0.34
MAPK10 P53779 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MAPT P10636 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
HTT P42858 2/20 0.33
TSHR P16473 2/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203541 0.90 SRC (0.38) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2853904 0.83 PKM (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2108014 0.83 PKM (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL202889 0.82 MAPK8 (0.45) SRCTGFBR1KMT2AMEN1MAPK8
SCHEMBL2853900 0.81 SRC (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2108015 0.81 SRC (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL2108009 0.81 SRC (0.36) PKMSRCTGFBR1KMT2AMEN1
SCHEMBL709625 0.77 ALDH1A1 (0.40) KMT2AMEN1NPSR1MAPTHTT
SCHEMBL7691499 0.76 POLB (0.39) GAASMN1; SMN2HCRTR1HCRTR2
SCHEMBL203516 0.76 RAF1 (0.39) KMT2AMEN1MAPK8MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 US disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 US disclosed
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF MERIAL, INC. 2010-09-30 US disclosed
WO-2005115704-A9 COMPOSITION FOR WOOD TREATMENT COMPRISING AN INJECTABLE AQUEOUS WOOD PRESERVATIVE SLURRY HAVING SPARINGLY-SOLUBLE BIOCIDAL PARTICLES AND PIGMENTS 2006-03-23 WO disclosed
WO-2005110692-A9 COMPOSITION, METHOD OF MAKING, AND TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES PHIBRO TECH INC (US) 2006-01-19 WO disclosed
WO-2005115704-A2 COMPOSITION FOR WOOD TREATMENT COMPRISING AN INJECTABLE AQUEOUS WOOD PRESERVATIVE SLURRY HAVING SPARINGLY-SOLUBLE BIOCIDAL PARTICLES AND PIGMENTS PHIBRO-TECH, INC. (US) 2005-12-08 WO disclosed
WO-2005110692-A2 COMPOSITION, METHOD OF MAKING, AND TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES PHIBRO-TECH, INC. (US) 2005-11-24 WO disclosed
US-20050255251-A1 Composition, method of making, and treatment of wood with an injectable wood preservative slurry having biocidal particles OSMOSE, INC 2005-11-17 US disclosed
WO-2005007368-A2 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME PHIBRO-TECH, INC. (US) 2005-01-27 WO disclosed
US-20050009883-A1 Fipronil and chloropyridine or chlorothiazole derivatives as antagonists of nicotinic acetylcholine receptors; protection of industrial materials and plants. UHR HERMANN (DE) 2005-01-13 US disclosed
US-20040258768-A1 An aqueous solution of injectable particles of sparingly soluble copper salts not easily leached, yet with sustained microbiocidal and insecticidal effectiveness; impregnation by injection OSMOSE, INC 2004-12-23 US disclosed
US-20030134857-A1 Synergistic insecticide mixtures UHR HERMANN (DE) 2003-07-17 US disclosed
US-6197799-B1 PLANT SAFENING AGENTS; PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 PKM 4121/4885SRC 1931/4885TGFBR1 1892/4885
US-20030134857-A1 Synergistic insecticide mixtures CHRM3, CHRNA5, CHRNA2 PKM 3701/4885SRC 2315/4885TGFBR1 310/4885
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 PKM 2740/4885SRC 3852/4885TGFBR1 3849/4885
US-20050009883-A1 Fipronil and chloropyridine or chlorothiazole derivatives as antagonists of nicotinic acetylcholine receptors; protection of industrial materials and plants. CHRM3, CHRNA5, CHRNE PKM 2533/4885SRC 2320/4885TGFBR1 469/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 PKM 1747/4885SRC 3148/4885TGFBR1 2497/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 PKM 4121/4885SRC 1931/4885TGFBR1 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.