SCHEMBL2108060

SCHEMBL2108060

CC=C(Oc1cc(Oc2ccccc2C#N)ncn1)C(=O)Oc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
MAP4K4 O95819 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
PIN1 Q13526 2/20 0.37
DHODH Q02127 1/20 0.37
MAPK14 Q16539 3/20 0.36
SYK P43405 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR5 Q9H1C0 1/20 0.34
DCK P27707 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
CYP3A4 P08684 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
SCN9A Q15858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27979372 0.91 POLB (0.38) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL8499271 0.82 MAP4K4 (0.39) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL24507690 0.77 MAP4K4 (0.56) POLBGAAMAP4K4PIN1MAPK14
SCHEMBL3958493 0.77 PIN1 (0.41) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL435487 0.77 PIN1 (0.41) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL55086 0.75 MAP4K4 (0.39) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL9065463 0.75 MAP4K4 (0.39) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL30852998 0.75 MAPK14 (0.39) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL9148647 0.75 MAPK14 (0.39) POLBGAAMAP4K4NPC1RAB9A
SCHEMBL5639516 0.74 SMN1; SMN2 (0.43) POLBGAAMAP4K4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed