Sugi Predict

Sugi Predict / Compounds / SCHEMBL55086

SCHEMBL55086

SCHEMBL55086

C/C=C(/C(=O)OC)c1ccccc1Oc1cc(Oc2ccccc2C#N)ncn1

nearest known ligand 0.84

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAP4K4 O95819 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ MAPK14 Q16539 3/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ SYK P43405 1/20 0.38
▸ PIN1 Q13526 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ MAPK1 P28482 1/20 0.37
▸ NPC1 O15118 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SCN9A Q15858 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ EZH2 Q15910 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065463 1.00 MAP4K4 (0.39) MAP4K4ALDH1A1HPGDTSHRMAPK14
SCHEMBL10045475 0.93 MAP4K4 (0.39) MAP4K4ALDH1A1HPGDTSHRMAPK14
SCHEMBL21389595 0.93 MAP4K4 (0.39) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL4447188 0.92 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL4113006 0.92 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL55087 0.92 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL29362394 0.92 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL18823 0.92 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL17701154 0.91 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
SCHEMBL21384537 0.90 ALDH1A1 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3004066-B1 PROCESS FOR PREPARING 4,6-BIS(ARYLOXY)PYRIMIDINE DERIVATIVES CHEMINOVA AS (DK) 2018-04-11 — — EP disclosed
US-9643935-B2 Process for preparing 4,6-BIS (aryloxy) pyrimidine derivatives CHEMINOVA A/S (DK) 2017-05-09 — — US disclosed
US-20160137612-A1 PROCESS FOR PREPARING 4,6-BIS (ARYLOXY) PYRIMIDINE DERIVATIVES CHEMINOVA A/S (DK) 2016-05-19 — — US disclosed
US-8877681-B2 Use of specific alcohol alkoxylates as an adjuvant for agrotechnical applications BASF SE (DE) 2014-11-04 — — US disclosed
US-8802120-B2 Bioactive agrichemical compositions and use thereof SCIESSENT LLC (US) 2014-08-12 — — US disclosed
US-8410021-B2 Compositions for the control of plant pests BAYER CROPSCIENCE AG (DE) 2013-04-02 — — US disclosed
US-20130012556-A1 Bioactive Agrichemical Compositions and Use Thereof SCIESSENT LLC (US) 2013-01-10 — — US disclosed
US-20120264607-A1 USE OF SPECIFIC ALCOHOL ALKOXYLATES AS AN ADJUVANT FOR AGROTECHNICAL APPLICATIONS BERGHAUS RAINER (DE) 2012-10-18 — — US disclosed
US-8287893-B2 Bioactive agrichemical compositions and use thereof SCIESSENT LLC (US) 2012-10-16 — — US disclosed
EP-2497363-A1 Bioactive agrichemical compositions and use thereof Sciessent, LLC (US) 2012-09-12 — — EP disclosed
US-6114363-A ACTIVITY AGAINST A BROAD SPECTRUM OF PHYTOPATHOGENIC FUNGI; COMPOUNDS SUCH AS N-METHYL-E-2-METHOXYIMINO-2-((2-(3-CHLORO-5-(PROP-1-EN-3-OXIMINOETH-1' -YL)PYRIDIN-2-YL))OXYMETHYL) PHENYL)ACETAMIDE BASF AKTIENGESELLSCHAFT (DE) 2000-09-05 — — US disclosed
US-6114342-A 2-(O-[pyrimidin-4-yl]methylenoxy)phenylacetic acid derivatives and their use for controlling harmful fungi and animal pests BASF AKTIENGESELLSCHAFT (DE) 2000-09-05 — — US disclosed
US-6075149-A FUNGICIDES, INSECTICIDEA AND PESTICIDES FOR PROTECTING CROPS BASF AKTIENGESELLSCHAFT (DE) 2000-06-13 — — US disclosed
US-6069144-A N-heterocyclic compounds, intermediate products used to prepare them, agents containing them and their use in antifungal applications BASF AKTIENGESELLSCHAFT (DE) 2000-05-30 — — US disclosed
US-6063813-A FUNGICIDES AND INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-05-16 — — US disclosed
US-6043282-A FUNGICIDES, PESTICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-03-28 — — US disclosed
US-5998450-A FOR PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-12-07 — — US disclosed
US-5977146-A Pyridylcarbamates, process and intermediates for their preparation, and their use BASF AKTIENGESELLSCHAFT (DE) 1999-11-02 — — US disclosed
US-5929119-A Fungicidal composition BASF AKTIENGESELLSCHAFT (DE) 1999-07-27 — — US disclosed
US-5847194-A Carbamoylcarboxamides BASF AKTIENGESELLSCHAFT (DE) 1998-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264607-A1 USE OF SPECIFIC ALCOHOL ALKOXYLATES AS AN ADJUVANT FOR AGROTECHNICAL APPLICATIONS ADH5, ALKBH3, ADH1C MAP4K4 3643/4885ALDH1A1 558/4885HPGD 831/4885
US-20160137612-A1 PROCESS FOR PREPARING 4,6-BIS (ARYLOXY) PYRIMIDINE DERIVATIVES NUDT1, UMPS, DPYD MAP4K4 660/4885ALDH1A1 1125/4885HPGD 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.