Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725057 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11726657 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11727025 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11727348 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11729895 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11729772 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11724194 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL10546875 | 0.98 | SPHK1 (0.44) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11730024 | 0.96 | SPHK1 (0.46) | SPHK1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL11729901 | 0.89 | EPHX2 (0.57) | EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158806-B2 | DAT1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2012-04-17 | — | — | US | disclosed |
| US-20090298177-A1 | DAT1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2009-12-03 | — | — | US | disclosed |
| US-20090018341-A1 | DAT1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2009-01-15 | — | — | US | disclosed |
| US-20080132709-A1 | Dat1 | DEPARTMENT OF BIOTECHNOLOGY (IN) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298177-A1 | DAT1 | TUBB1, TUBB6, TUBB | SPHK1 3995/4885EPHX1 4181/4885EPHX2 4664/4885 |
| US-20090018341-A1 | DAT1 | TUBB1, TUBB6, TUBB | SPHK1 3995/4885EPHX1 4181/4885EPHX2 4664/4885 |
| US-20080132709-A1 | Dat1 | TUBB1, TUBB6, TUBB | SPHK1 3995/4885EPHX1 4181/4885EPHX2 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.