SCHEMBL21082016

SCHEMBL21082016

O=C(C=Cc1ccccc1)Nc1ccccc1NC(=O)Nc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 13/20 0.73
MMP2 P08253 13/20 0.73
MMP9 P14780 13/20 0.73
EGFR P00533 9/20 0.73
MAOB P27338 2/20 0.73
MAOA P21397 1/20 0.73
DEGS1 O15121 1/20 0.60
HDAC1 Q13547 1/20 0.58
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19501046 1.00 MMP1 (0.73) MMP1MMP2MMP9EGFRMAOB
SCHEMBL19501838 0.89 MMP1 (0.86) MMP1MMP2MMP9EGFRMAOB
SCHEMBL10492424 0.88 MMP1 (0.80) MMP1MMP2MMP9EGFRMAOB
SCHEMBL10492426 0.88 MMP1 (0.80) MMP1MMP2MMP9EGFRMAOB
SCHEMBL1959389 0.86 MMP1 (0.70) MMP1MMP2MMP9EGFRMAOB
SCHEMBL530137 0.86 MMP1 (0.70) MMP1MMP2MMP9EGFRMAOB
N-Phenylcinnamamide SCHEMBL3667414 0.85 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
N-Phenylcinnamamide SCHEMBL4205896 0.85 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
N-Phenylcinnamamide SCHEMBL2682029 0.85 MMP1 (1.00) MMP1MMP2MMP9EGFRMAOB
SCHEMBL19501005 0.84 MMP1 (0.78) MMP1MMP2MMP9EGFRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3505357-B1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO (JP) 2022-06-29 EP disclosed
US-11142015-B2 Recording material, and recording sheet NIPPON SODA CO., LTD. (JP) 2021-10-12 US disclosed
US-20200180335-A1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO., LTD. (JP) 2020-06-11 US disclosed
EP-3505357-A1 RECORDING MATERIAL AND RECORDING SHEET Nippon Soda Co., Ltd. (JP) 2019-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200180335-A1 RECORDING MATERIAL AND RECORDING SHEET SCN1A, SCN1B, SCN2A MMP1 1234/4885MMP2 1596/4885MMP9 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.