Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 5/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437314 | 0.86 | APP (0.39) | THRBHTTMEN1KMT2ARARB | |
| SCHEMBL21083150 | 0.79 | THRB (0.42) | THRBHTTRARBALDH1A1CYP3A4 | |
| SCHEMBL3437310 | 0.79 | CA12 (0.44) | THRBMEN1KMT2ARARBCA12 | |
| SCHEMBL21556844 | 0.79 | THRB (0.40) | THRBHTTPTPN11CA12CA1 | |
| SCHEMBL815645 | 0.78 | THRB (0.47) | THRBHTTRARBPTPN11CA12 | |
| SCHEMBL20414537 | 0.78 | APP (0.41) | THRBMEN1KMT2ACA12CA1 | |
| SCHEMBL21242268 | 0.77 | ALDH1A1 (0.53) | THRBHTTRARBALDH1A1CYP3A4 | |
| SCHEMBL20414530 | 0.77 | APP (0.40) | THRBMEN1KMT2ACA12CA1 | |
| SCHEMBL20929817 | 0.77 | KMT2A (0.41) | THRBHTTKMT2ACA12CA1 | |
| SCHEMBL3437308 | 0.75 | CA12 (0.49) | THRBMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173457-B1 | LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2019-06-05 | — | — | EP | disclosed |