Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | TPH1 | P17752 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270611 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22689706 | 0.88 | LTA4H (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22689704 | 0.88 | LTA4H (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22690112 | 0.85 | LTA4H (0.51) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22690114 | 0.85 | LTA4H (0.51) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22442195 | 0.84 | NOS3 (0.49) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22442196 | 0.84 | NOS3 (0.49) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL12835439 | 0.84 | ALDH1A1 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL22689686 | 0.84 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL21083181 | 0.84 | MAPT (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12359192-B2 | Methods and compositions for display of macrocyclic peptides | UNIVERSITY OF ROCHESTER (US) | 2025-07-15 | — | — | US | claimed |
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2025-06-19 | — | — | US | claimed |
| WO-2023173084-A9 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023173084-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-09-14 | — | — | WO | claimed |
| US-20200299675-A1 | Methods and Compositions for Display of Macrocyclic Peptides | UNIVERSITY OF ROCHESTER | 2020-09-24 | — | — | US | claimed |
| US-12460317-B2 | Genetically encoded, phage-displayed cyclic peptide library and methods of making the same | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2025-11-04 | — | — | US | disclosed |
| US-12359192-B2 | Methods and compositions for display of macrocyclic peptides | UNIVERSITY OF ROCHESTER (US) | 2025-07-15 | — | — | US | disclosed |
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2025-06-19 | — | — | US | disclosed |
| WO-2023173084-A9 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023173084-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-09-14 | — | — | WO | disclosed |
| US-20230139680-A1 | A GENETICALLY ENCODED, PHAGE-DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF MAKING THE SAME | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2023-05-04 | — | — | US | disclosed |
| CN-113727725-A | Genetically encoded phage-displayed cyclic peptide libraries and methods of making the same | 得克萨斯A&M大学系统 | 2021-11-30 | — | — | CN | disclosed |
| US-20200299675-A1 | Methods and Compositions for Display of Macrocyclic Peptides | UNIVERSITY OF ROCHESTER | 2020-09-24 | — | — | US | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139680-A1 | A GENETICALLY ENCODED, PHAGE-DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF MAKING THE SAME | QPCTL, LNPEP, QPCT | SLC7A5 1345/4885SLC1A3 696/4885SLC1A2 648/4885 |
| US-12359192-B2 | Methods and compositions for display of macrocyclic peptides | NGLY1, MICA, MRPL21 | SLC7A5 1926/4885SLC1A3 4116/4885SLC1A2 4263/4885 |
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | FCGR3B, FCGRT, FCGR2A | SLC7A5 2011/4885SLC1A3 2513/4885SLC1A2 3193/4885 |
| US-20200299675-A1 | Methods and Compositions for Display of Macrocyclic Peptides | SPOUT1, NGLY1, VIP | SLC7A5 1358/4885SLC1A3 3561/4885SLC1A2 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.