Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 7/20 | 0.44 |
| ▸ | NOS1 | P29475 | 5/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826645 | 1.00 | GSR (0.50) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL10238195 | 0.98 | GSR (0.52) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL826933 | 0.93 | GSR (0.48) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL5668298 | 0.93 | GSR (0.48) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL231631 | 0.93 | GSR (0.48) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL19417862 | 0.86 | GSR (0.46) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL15634459 | 0.85 | GSR (0.45) | GSRARG2ARG1CYP1A2BLM | |
| SCHEMBL826512 | 0.85 | GSR (0.45) | GSRARG2ARG1CYP1A2BLM | |
| SCHEMBL12905680 | 0.82 | NOS2 (0.34) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL18713274 | 0.80 | GSR (0.41) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389145-A2 | INTERLEUKIN-2 POLYPEPTIDE CONJUGATES AND THEIR USES | Ambrx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| EP-2605789-B1 | MODIFIED RELAXIN POLYPEPTIDES AND THEIR USES | AMBRX INC (US) | 2019-06-05 | — | — | EP | disclosed |