Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295879 | 1.00 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1ALDH1A1MEN1 | |
| SCHEMBL11118223 | 0.85 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1GRIK1TDP1 | |
| SCHEMBL10984272 | 0.82 | ACE (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10984275 | 0.82 | ACE (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9978454 | 0.80 | MEN1 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10836004 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL10836000 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL10654908 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL10965683 | 0.78 | FNTA (0.48) | ALDH1A1MEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL10965678 | 0.78 | FNTA (0.48) | ALDH1A1MEN1KMT2AGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158393-B2 | Polypeptide having esterase activity and recombinant esterase and use thereof | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AU) | 2012-04-17 | — | — | US | disclosed |