SCHEMBL8911079

SCHEMBL8911079

O=C(c1ccccc1)C1C=CC(Oc2ccccc2)(Oc2ccccc2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
HBB P68871 1/20 0.36
EPHX1 P07099 1/20 0.35
AKR1C3 P42330 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
F2 P00734 1/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 3/20 0.33
CES1 P23141 3/20 0.33
CES2 O00748 2/20 0.33
DAO P14920 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1627984 0.90 MAOA (0.36) HTTMAPTALOX15HBBSMN1; SMN2
Ammonia Solution, Strong SCHEMBL10582921 0.88 MAOA (0.35) HTTMAPTALOX15HBBSMN1; SMN2
SCHEMBL9750703 0.86 PBRM1 (0.42) MAPTAKR1C3SMN1; SMN2LMNATP53
SCHEMBL5267430 0.83 POLB (0.48) HTTAKR1C3LMNAPOLBHSD17B10
SCHEMBL10893912 0.83 TDP1 (0.42) MAPTSMN1; SMN2CES1CES2TP53
SCHEMBL210844 0.81 TSHR (0.41) HTTMAPTALOX15HBBEPHX1
SCHEMBL5927265 0.81 MAPT (0.36) HTTMAPTSMN1; SMN2LMNAPOLB
SCHEMBL10586101 0.79 ELANE (0.38) HTTMAPTALOX15HBBEPHX1
SCHEMBL17042559 0.78 ALDH1A1 (0.36) HTTMAPTALOX15HBBEPHX1
SCHEMBL136598 0.77 MAPT (0.41) HTTMAPTALOX15HBBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262920-B1 PREPARATION OF ARYLENE OLIGOMERS RAYCHEM LIMITED (GB) 1993-04-07 EP claimed
JP-2189332-A None JP disclosed
US-5612451-A Amphoteric metal oxides as cocatalyst in the electrophilic synthesis of polyaryl ether ketones BASF AKTIENGESELLSCHAFT (DE) 1997-03-18 US disclosed
US-5580948-A Preparation of polyarylene ether ketones BASF AKTIENGESELLSCHAFT (DE) 1996-12-03 US disclosed
EP-0692508-A1 Cocatalyst based on amphoteric metal oxides for the electrophylic synthesis of polyarylene ether ketones BASF AKTIENGESELLSCHAFT (DE) 1996-01-17 EP disclosed
EP-0638603-A2 Process for the production of polyarylene ether ketones BASF Aktiengesellschaft (DE) 1995-02-15 EP disclosed
US-5084530-A Polyether ketone resins for molding materials and extrusion composites AMOCO CORPORATION (US) 1992-01-28 US disclosed
EP-0407386-A1 PREPARATION OF POLY(ARYLENE ETHER KETONES) RAYCHEM LIMITED (GB) 1991-01-16 EP disclosed
US-4968758-A MOLODING MATERIALS WITH EXCELLENT HEAT, SOLVENT, AND STRESS-CRACK RESISTANCE AMOCO CORPORATION (US) 1990-11-06 US disclosed
JP-H02189332-A PRODUCTION OF AROMATIC POLY(THIO)ETHER KETONE SHOWA DENKO KK 1990-07-25 JP disclosed
WO-1989004848-A1 PREPARATION OF POLY(ARYLENE ETHER KETONES) RAYCHEM LIMITED (GB) 1989-06-01 WO disclosed