Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 10/20 | 0.80 |
| ▸ | FLT1 | P17948 | 9/20 | 0.80 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.80 |
| ▸ | CSF1R | P07333 | 3/20 | 0.80 |
| ▸ | FLT4 | P35916 | 3/20 | 0.80 |
| ▸ | GSK3A | P49840 | 2/20 | 0.80 |
| ▸ | GSK3B | P49841 | 2/20 | 0.80 |
| ▸ | SRC | P12931 | 2/20 | 0.80 |
| ▸ | EGFR | P00533 | 1/20 | 0.80 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.80 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.80 |
| ▸ | CDK2 | P24941 | 1/20 | 0.80 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.80 |
| ▸ | KDR | P35968 | 9/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.61 |
| ▸ | KIT | P10721 | 4/20 | 0.59 |
| ▸ | FLT3 | P36888 | 3/20 | 0.59 |
| ▸ | AURKA | O14965 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | LCK | P06239 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw770249X SCHEMBL30957039 | 0.89 | TEK (1.00) | TEKFLT1RIPK1CSF1RFLT4 | |
| Gw770249X SCHEMBL5652411 | 0.89 | TEK (1.00) | TEKFLT1RIPK1CSF1RFLT4 | |
| Gw770249X SCHEMBL29638046 | 0.89 | TEK (1.00) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL25008891 | 0.82 | FLT1 (0.87) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL3524617 | 0.78 | TEK (0.75) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL13708284 | 0.76 | KDR (0.80) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL3113394 | 0.74 | KDR (1.00) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL546436 | 0.74 | KIT (1.00) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL30055372 | 0.74 | KIT (1.00) | TEKFLT1RIPK1CSF1RFLT4 | |
| SCHEMBL24710786 | 0.74 | FLT1 (0.71) | TEKFLT1RIPK1CSF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053454-B2 | Compositions for cryopreservation and methods of use thereof | EVERGREEN BIOSCIENCES (US) | 2024-08-06 | — | — | US | disclosed |
| US-20190201381-A1 | COMPOSITIONS FOR CRYOPRESERVATION AND METHODS OF USE THEREOF | EVERGREEN BIOSCIENCES (US) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053454-B2 | Compositions for cryopreservation and methods of use thereof | BAK1, BAX, BAD | TEK 4326/4885FLT1 4124/4885RIPK1 12/4885 |
| US-20190201381-A1 | COMPOSITIONS FOR CRYOPRESERVATION AND METHODS OF USE THEREOF | BAX, BAK1, CASP3 | TEK 2662/4885FLT1 3859/4885RIPK1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.