Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049390 | 0.90 | ALDH1A1 (0.77) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL673569 | 0.82 | ALDH1A1 (0.74) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL8281830 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL13434151 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL9386712 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL12071217 | 0.77 | LMNA (0.57) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL20183040 | 0.76 | KMT2A (0.60) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL20183041 | 0.76 | KMT2A (0.60) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL11870023 | 0.76 | KMT2A (0.60) | ALDH1A1GAAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL4710707 | 0.75 | POLB (0.56) | ALDH1A1GAAKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019130346-A1 | NOVEL PHENOLIC COMPOUNDS FROM NERIUM INDICUM WITH ANTI-BREAST CANCER ACTIVITY | K SYED ZAMEER AHMED (IN) | 2019-07-04 | — | — | WO | disclosed |