Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715728 | 0.82 | IDO1 (0.59) | FFAR1FFAR4IDO1AGXTNR3C1 | |
| SCHEMBL3641589 | 0.82 | NR3C1 (0.43) | FFAR1FFAR4IDO1AGXTNR3C1 | |
| SCHEMBL29506809 | 0.82 | NR3C1 (0.43) | FFAR1FFAR4IDO1AGXTNR3C1 | |
| Hydrochloric Acid SCHEMBL1715723 | 0.81 | IDO1 (0.61) | FFAR1FFAR4IDO1AGXTNR3C1 | |
| SCHEMBL14625917 | 0.79 | FFAR1 (0.42) | FFAR1FFAR4NR3C1PGRNR3C2 | |
| SCHEMBL15018170 | 0.79 | FFAR1 (0.45) | FFAR1FFAR4NR3C1PGRNR3C2 | |
| SCHEMBL29924288 | 0.79 | FFAR1 (0.45) | FFAR1FFAR4NR3C1PGRNR3C2 | |
| SCHEMBL25404947 | 0.79 | RORC (0.38) | FFAR1FFAR4IDO1AGXTNR3C1 | |
| SCHEMBL23286837 | 0.79 | FFAR1 (0.40) | FFAR1FFAR4IDO1AGXTNR3C1 | |
| SCHEMBL19745238 | 0.78 | MAOB (0.51) | FFAR1FFAR4CYP19A1CTSBPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492464-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Sciences, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |