Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768202 | 0.76 | HTR2A (0.52) | FFAR4HTR2APKMNPSR1 | |
| SCHEMBL659978 | 0.74 | LMNA (0.34) | FFAR4PKMNPSR1CTSAIDO1 | |
| SCHEMBL657523 | 0.72 | HTR2A (0.33) | FFAR4HTR2AIDO1 | |
| SCHEMBL19307517 | 0.72 | FFAR4 (1.00) | FFAR4 | |
| SCHEMBL17593060 | 0.72 | FFAR4 (1.00) | FFAR4 | |
| SCHEMBL20032739 | 0.72 | FFAR4 (0.85) | FFAR4HTR2A | |
| SCHEMBL11253181 | 0.72 | FFAR4 (0.33) | FFAR4HTR2A | |
| SCHEMBL19294276 | 0.71 | FFAR4 (0.56) | FFAR4HTR2APKMNPSR1CTSA | |
| SCHEMBL4750485 | 0.71 | HTR2A (0.51) | FFAR4HTR2APKMNPSR1 | |
| SCHEMBL1005341 | 0.71 | HTR2A (0.51) | FFAR4HTR2APKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191445-B1 | CYCLOBUTANE CONTAINING CARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-12 | — | — | EP | disclosed |