Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21087342 | 0.72 | FFAR4 (0.55) | FFAR4HTR2A | |
| SCHEMBL17269667 | 0.69 | AKT1 (0.41) | HTR2A | |
| SCHEMBL11266547 | 0.66 | RHEB (0.31) | — | |
| SCHEMBL30888630 | 0.65 | AKT1 (0.42) | FFAR4HTR2A | |
| SCHEMBL11268590 | 0.65 | — | — | |
| SCHEMBL11262388 | 0.64 | AMY1A (0.37) | MAPT | |
| SCHEMBL11259880 | 0.64 | AMY1A (0.51) | MAPTNPC1RAB9A | |
| SCHEMBL11253114 | 0.64 | AMY1A (0.47) | MAPTNPC1RAB9A | |
| SCHEMBL11251284 | 0.64 | HTR2A (0.32) | FFAR4HTR2A | |
| SCHEMBL669624 | 0.64 | FFAR4 (0.38) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |