SCHEMBL2108796

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4635873	0.91	TOP2B (0.54)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL6814600	0.91	TOP2B (0.54)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL9890823	0.90	TOP2B (0.55)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL2090426	0.90	MAOA (0.62)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL6341335	0.90	MAOA (0.62)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL2088401	0.89	TOP2B (0.55)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL6805751	0.89	TOP2B (0.52)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL29433777	0.89	TOP2B (0.52)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL4635171	0.89	TOP2B (0.52)	TOP2BKDM4EALDH1A1LMNAHPGD
	SCHEMBL702285	0.89	TOP2B (0.52)	TOP2BKDM4EALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.