Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17316588 | 0.76 | DRD2 (0.49) | SLC6A4DRD2GSK3BTUBB4ATUBB | |
| SCHEMBL12127887 | 0.75 | DRD2 (0.48) | SLC6A4DRD2GSK3BTUBB4ATUBB | |
| SCHEMBL9764630 | 0.74 | DRD2 (0.53) | SLC6A4DRD2GSK3BRORC | |
| SCHEMBL21088053 | 0.73 | APP (0.50) | SLC6A4DRD2GSK3BTUBB4ATUBB | |
| SCHEMBL2417482 | 0.66 | IMPDH2 (0.59) | SLC6A4GSK3BKRAS | |
| SCHEMBL29104115 | 0.64 | GSK3B (0.43) | SLC6A4DRD2GSK3BTUBB4ATUBB | |
| SCHEMBL12127417 | 0.64 | SCN9A (0.57) | SLC6A4DRD2TUBB4ATUBBTUBA3C | |
| SCHEMBL12127458 | 0.64 | DRD2 (0.56) | SLC6A4DRD2 | |
| SCHEMBL13035740 | 0.63 | CSNK2A1 (0.48) | GSK3BCYP19A1KRAS | |
| SCHEMBL12131801 | 0.63 | APP (0.59) | SLC6A4DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558446-B1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2019-06-12 | — | — | EP | disclosed |