⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847938 | 0.69 | — | — | |
| SCHEMBL8271340 | 0.63 | — | — | |
| SCHEMBL18633477 | 0.61 | — | — | |
| SCHEMBL17793593 | 0.60 | — | — | |
| SCHEMBL22416532 | 0.58 | MRGPRX2 (0.37) | — | |
| SCHEMBL18137049 | 0.57 | — | — | |
| SCHEMBL12030675 | 0.56 | — | — | |
| SCHEMBL17733591 | 0.56 | MRGPRX2 (0.38) | — | |
| SCHEMBL22264961 | 0.56 | — | — | |
| SCHEMBL11928883 | 0.54 | MRGPRX2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558446-B1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2019-06-12 | — | — | EP | disclosed |