Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BAX | Q07812 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421733 | 0.78 | LTA4H (0.48) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL21548080 | 0.78 | LTA4H (0.41) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL13289 | 0.75 | LTA4H (0.50) | LTA4HTSHRCA4MAOACA1 | |
| Iodide SCHEMBL5553135 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL8662152 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL3009883 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL8113527 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL19327377 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL16415989 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 | |
| SCHEMBL11681119 | 0.73 | LTA4H (0.47) | LTA4HTSHRCA4MAOACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586312-A | Preparation method of hexaphenoxy cyclotriphosphazene and catalyst thereof | 国磷(上海)阻燃材料有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-113773502-A | Diphenylphosphinic amide silicone oil flame retardant and preparation method thereof | 常州大学 | 2021-12-10 | — | — | CN | claimed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117586312-A | Preparation method of hexaphenoxy cyclotriphosphazene and catalyst thereof | 国磷(上海)阻燃材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586312-A | Preparation method of hexaphenoxy cyclotriphosphazene and catalyst thereof | 国磷(上海)阻燃材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-112236423-B | Piperidinyl-3- (aryloxy) propanamides and propionic acid esters | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| CN-113773502-B | Diphenyl phosphinic amide silicone oil fire retardant and its preparation method | 常州大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-113195720-A | Enzymatic RNA synthesis | 哈佛大学的校长及成员们 | 2021-07-30 | — | — | CN | disclosed |
| CN-112236417-A | Cyanoquinoline amide compounds as HER2 inhibitors and methods of use | 达纳-法伯癌症研究所股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-112236423-A | Piperidinyl-3- (aryloxy) propanamides and propionates | 武田药品工业株式会社 | 2021-01-15 | — | — | CN | disclosed |
| CN-112020358-A | Small molecules inducing selective degradation of proteins and uses thereof | 达纳-法伯癌症研究所有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-105849099-B | Polycyclic inhibitors of cyclin dependent kinase 7(CDK7) | 达纳-法伯癌症研究所股份有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698460-A | Heteroaryl compound, preparation method, pharmaceutical composition and application thereof | 隆泰申医药科技(南京) 有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-109136974-B | C (sp) -containing2) Process for producing (E) -N bond compound | 中国科学院上海有机化学研究所 | 2019-12-31 | — | — | CN | disclosed |
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| CN-109136974-A | One kind (sp containing C2)-N key compound preparation method | 中国科学院上海有机化学研究所 | 2019-01-04 | — | — | CN | disclosed |
| CN-105849099-A | Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7) | 达纳-法伯癌症研究所股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-102596220-A | Monophosphorylated lipid A derivatives | UNIV WAYNE STATE | 2012-07-18 | — | — | CN | disclosed |