SCHEMBL21548080

SCHEMBL21548080

NP(O)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
TSHR P16473 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
CA4 P22748 1/20 0.38
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
MAOA P21397 1/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
CA9 Q16790 1/20 0.36
SRC P12931 1/20 0.36
PARP10 Q53GL7 1/20 0.35
KCNA3 P22001 1/20 0.35
ALOX15 P16050 1/20 0.34
MAOB P27338 1/20 0.33
CTNNB1 P35222 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862133 0.86 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL126344 0.78 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL30275406 0.78 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL21088680 0.78 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL132913 0.78 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL27572063 0.78 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL30883096 0.78 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL23754601 0.76 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL1160536 0.76 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Hydrochloric Acid SCHEMBL11619305 0.76 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036790-A Chiral phosphine-acyclic phosphoramidite ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2026-05-15 CN claimed
CN-122036790-A Chiral phosphine-acyclic phosphoramidite ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2026-05-15 CN disclosed
EP-3564240-A1 PIPERIDINE INTERMEDIATES Purdue Pharma L.P. (US) 2019-11-06 EP disclosed