Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15915417 | 0.79 | HTR7 (0.42) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL25142154 | 0.74 | MYC (0.40) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL23259470 | 0.72 | MAOA (0.46) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL3831544 | 0.72 | HTR7 (0.39) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL31171603 | 0.72 | HTR7 (0.39) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL2951109 | 0.70 | MAOA (0.40) | MAOAMAOBLMNAALDH1A1CYP1A2 | |
| SCHEMBL17899831 | 0.70 | HTR7 (0.38) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL24199390 | 0.69 | MAOA (0.43) | HTR7MAOAMAOBLMNAALDH1A1 | |
| SCHEMBL9995022 | 0.69 | SLC22A12 (0.51) | — | |
| SCHEMBL20627452 | 0.67 | ESR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |