Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088591 | 0.78 | NAMPT (0.62) | — | |
| SCHEMBL8392199 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HTTRAB9ACYP2C19NPC1 | |
| SCHEMBL20627310 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1HPGDKMT2ALMNAHTT | |
| SCHEMBL9461062 | 0.74 | EPHX1 (0.51) | ALDH1A1HPGDKMT2ALMNAHTT | |
| SCHEMBL4190698 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2ALMNASMN1; SMN2 | |
| SCHEMBL23795440 | 0.74 | EPHX1 (0.59) | ALDH1A1HPGDKMT2ALMNAHTT | |
| SCHEMBL830513 | 0.73 | EPHX1 (0.66) | ALDH1A1HPGDKMT2ALMNAHTT | |
| SCHEMBL21089377 | 0.73 | NAMPT (0.56) | — | |
| SCHEMBL829484 | 0.72 | NCEH1 (0.62) | HPGDHTTSMN1; SMN2MAPTRAB9A | |
| SCHEMBL8393242 | 0.72 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |