Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12129057 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL24510844 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL13893426 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL1043645 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL28214132 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALIMK1 | |
| SCHEMBL4455128 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL29960515 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL224028 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13039531 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5476580 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558446-B1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE SA (CH) | 2019-06-12 | — | — | EP | disclosed |