Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960515 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AMEN1KCNA5 | |
| SCHEMBL4098064 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AMEN1KCNA5 | |
| SCHEMBL18993220 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1IDO1 | |
| SCHEMBL18599498 | 0.82 | KCNA5 (0.53) | ALDH1A1MAPTKMT2AMEN1KCNA5 | |
| SCHEMBL12129057 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL10191908 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1KCNA5 | |
| SCHEMBL953597 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1KCNA5 | |
| SCHEMBL27599896 | 0.78 | KMT2A (0.68) | ALDH1A1MAPTKMT2AMEN1IDO1 | |
| SCHEMBL224027 | 0.76 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1KCNA5 | |
| SCHEMBL6351856 | 0.76 | MAPT (0.66) | ALDH1A1MAPTKMT2AMEN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| CN-114890856-B | Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative | 华南理工大学 | 2023-08-22 | — | — | CN | disclosed |
| US-20220413384-A1 | PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2022-12-29 | — | — | US | disclosed |
| US-20220143012-A1 | Macromolecule-Supported TLR Agonists | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-05-12 | — | — | US | disclosed |
| US-9540392-B2 | Thienopyrimidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-01-10 | — | — | US | disclosed |
| US-9540392-B2 | Thienopyrimidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-01-10 | — | — | US | disclosed |
| EP-2852596-B1 | THIENOPYRIMIDINES | Bayer Pharma AG (DE) | 2016-06-22 | — | — | EP | disclosed |
| EP-2354187-B1 | DISPERSED COMPOSITION, POLYMERIZABLE COMPOSITION, LIGHT SHIELDING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, LIQUID CRYSTAL DISPLAY DEVICE, WAFER-LEVEL LENS, AND IMAGING UNIT | FUJIFILM CORP (JP) | 2016-03-02 | — | — | EP | disclosed |
| US-9110205-B2 | Black curable composition, light-shielding color filter, light-shielding film and method for manufacturing the same, wafer level lens, and solid-state imaging device | FUJIFILM CORPORATION (JP) | 2015-08-18 | — | — | US | disclosed |
| US-6316605-B1 | FOR USE IN RECORDING MATERIALS FOR THERMAL TRANSFER RECORDING, INK JET RECORDING | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6228553-B1 | SHELF LIFE, STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |
| US-5925489-A | CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| EP-0710241-A1 | NOVEL SILYLATED BENZYLAMINE DERIVATIVES, SALTS THEREOF, METHODS OF MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PIERRE FABRE MEDICAMENT (FR) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003313-A1 | NOVEL SILYLATED BENZYLAMINE DERIVATIVES, SALTS THEREOF, METHODS OF MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PIERRE FABRE MEDICAMENT (FR) | 1995-02-02 | — | — | WO | disclosed |
| EP-0000602-B1 | PROCESS FOR THE PREPARATION OF ISOCYANATES FROM FORMAMIDES | AKZO N.V. (NL) | 1981-07-22 | — | — | EP | disclosed |
| US-4207251-A | Catalytic oxidation of formamides to form isocyanates | AKZONA INCORPORATED (US) | 1980-06-10 | — | — | US | disclosed |
| EP-0000602-A1 | Process for the preparation of isocyanates from formamides | AKZO N.V. (NL) | 1979-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143012-A1 | Macromolecule-Supported TLR Agonists | TLR8, TLR7, TLR9 | ALDH1A1 2748/4885MAPT 3090/4885KMT2A 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.