Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056584 | 0.91 | HDAC1 (0.59) | HDAC1HRH3POLBSSTR3KMT2A | |
| SCHEMBL8807024 | 0.86 | HDAC1 (0.67) | HDAC1HRH3POLBKMT2ACXCR4 | |
| SCHEMBL9068606 | 0.85 | SSTR3 (0.72) | HDAC1SSTR3KMT2AMEN1ALDH1A1 | |
| SCHEMBL791504 | 0.84 | CHEK1 (0.54) | HDAC1SSTR3KMT2AHPGDMEN1 | |
| SCHEMBL10953965 | 0.84 | HRH3 (0.88) | HDAC1HRH3POLBKMT2ACXCR4 | |
| SCHEMBL18172536 | 0.83 | HDAC1 (0.51) | HDAC1HRH3POLBSSTR3KMT2A | |
| SCHEMBL21088372 | 0.83 | HDAC1 (0.67) | HDAC1HRH3POLBKMT2ACXCR4 | |
| SCHEMBL18172538 | 0.83 | HDAC1 (0.51) | HDAC1HRH3POLBSSTR3KMT2A | |
| SCHEMBL18023358 | 0.83 | HDAC1 (0.51) | HDAC1HRH3SSTR3KMT2AMEN1 | |
| SCHEMBL21088517 | 0.81 | PPM1D (0.57) | HDAC1HRH3POLBCXCR4EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |