Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520931 | 0.77 | IDO1 (1.00) | IDO1TAAR1PARP10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1715773 | 0.75 | IDO1 (1.00) | IDO1TAAR1PARP10 | |
| Hydrochloric Acid SCHEMBL1715477 | 0.75 | IDO1 (1.00) | IDO1TAAR1PARP10 | |
| SCHEMBL3865796 | 0.72 | IDO1 (0.67) | IDO1TAAR1PARP10ALDH1A1MAPT | |
| SCHEMBL11513287 | 0.72 | IDO1 (0.67) | IDO1TAAR1PARP10ALDH1A1MAPT | |
| SCHEMBL13386702 | 0.72 | IDO1 (0.50) | IDO1TAAR1PARP10ALDH1A1MAPT | |
| SCHEMBL28808714 | 0.72 | PARP10 (0.51) | IDO1TAAR1PARP10ALDH1A1MAPT | |
| SCHEMBL20626905 | 0.70 | IDO1 (0.48) | IDO1TAAR1PARP10ALDH1A1MAPT | |
| SCHEMBL8769614 | 0.69 | IDO1 (0.47) | IDO1TAAR1PARP10ALDH1A1MAPT | |
| SCHEMBL8703610 | 0.69 | TAAR1 (0.64) | IDO1TAAR1PARP10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |