Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808714 | 0.78 | PARP10 (0.51) | IDO1ALDH1A1PARP10RIPK1MAPT | |
| SCHEMBL8691537 | 0.77 | NPC1 (0.59) | RAB9A | |
| SCHEMBL394807 | 0.76 | RIPK1 (0.65) | ALDH1A1RIPK1MAPTKMT2ARAB9A | |
| SCHEMBL9812396 | 0.76 | MMP1 (0.49) | IDO1ALDH1A1PARP10RIPK1MAPT | |
| SCHEMBL29789854 | 0.73 | TAAR1 (0.50) | ALDH1A1RIPK1KMT2APOLBTAAR1 | |
| SCHEMBL3533334 | 0.73 | TAAR1 (0.50) | ALDH1A1RIPK1KMT2APOLBTAAR1 | |
| SCHEMBL114463 | 0.69 | PARP10 (0.57) | IDO1ALDH1A1PARP10MAPTKMT2A | |
| SCHEMBL21089401 | 0.69 | IDO1 (0.62) | IDO1ALDH1A1PARP10MAPTKMT2A | |
| SCHEMBL10800307 | 0.69 | ALDH1A1 (0.56) | IDO1ALDH1A1PARP10RIPK1MAPT | |
| SCHEMBL28269575 | 0.69 | CES1 (0.55) | ALDH1A1RIPK1KMT2ARAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792870-A1 | Process for the preparation of ketoximethers by coupling with boronic acid derivatives | Hoechst Schering AgrEvo GmbH (DE) | 1997-09-03 | — | — | EP | disclosed |