SCHEMBL2108962

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13731115	0.80	P4HTM (0.64)	MAP4K4P4HA1MIFP4HTMKDM4E
	SCHEMBL2109080	0.80	GSK3B (0.51)	CCNCCDK8USP30MKNK1MKNK2
	SCHEMBL1222255	0.78	CHEK1 (0.70)	CCNCCDK8MAP4K4CHEK1PIM1
	SCHEMBL23559705	0.78	IKBKE (0.50)	USP30KDM4EABL1
	SCHEMBL10328709	0.77	CHEK1 (0.50)	CCNCCDK8MAP4K4USP30CHEK1
	SCHEMBL25424542	0.77	HPGDS (0.58)	MAP4K4ALDH1A1MAPT
	SCHEMBL22534369	0.76	STING1 (0.60)	CCNCCDK8MAP4K4CHEK1PIM1
	SCHEMBL30519697	0.76	MAPT (0.47)	MAP4K4USP30CHEK1PIM1PIM2
	SCHEMBL27252273	0.76	MAPT (0.47)	MAP4K4USP30CHEK1PIM1PIM2
	SCHEMBL21033716	0.76	CCNC (0.46)	CCNCCDK8MAP4K4USP30CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.