Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 20/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 15/20 | 0.59 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.59 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089527 | 0.92 | KCNQ2 (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL21132316 | 0.86 | KCNQ2 (0.57) | KCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL21089646 | 0.82 | KCNQ3 (0.43) | KCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL21089525 | 0.76 | KCNQ3 (0.40) | KCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL321477 | 0.74 | KCNQ3 (1.00) | KCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL21089532 | 0.72 | KCNQ2 (0.57) | KCNQ2KCNQ3 | |
| SCHEMBL21051214 | 0.70 | KCNQ2 (0.73) | KCNQ2KCNQ3 | |
| SCHEMBL22062264 | 0.70 | KCNQ3 (0.42) | KCNQ2KCNQ3KCNQ4KCNQ5 | |
| SCHEMBL31322183 | 0.66 | KCNQ2 (0.59) | KCNQ2 | |
| SCHEMBL21051220 | 0.65 | L3MBTL1 (0.45) | KCNQ2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676437-B2 | Fluorinated 4-(substituted amino)phenyl carbamate derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2020-06-09 | — | — | US | disclosed |
| WO-2019118657-A1 | FLUORINATED 4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| US-20190177274-A1 | FLUORINATED 4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10676437-B2 | Fluorinated 4-(substituted amino)phenyl carbamate derivatives | KCNQ2, KCNQ1, KCNN3 | KCNQ2 1/4885KCNQ3 4/4885KCNQ4 6/4885 |
| US-20190177274-A1 | FLUORINATED 4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNN3 | KCNQ2 1/4885KCNQ3 4/4885KCNQ4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.