Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 5/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089921 | 0.87 | KCNQ2 (0.68) | KCNQ2 | |
| SCHEMBL21089552 | 0.85 | KCNQ2 (0.52) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL31020108 | 0.77 | KCNQ2 (0.73) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19698798 | 0.76 | KCNQ2 (0.54) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL19708173 | 0.74 | KCNQ2 (0.52) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL21089913 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL21089649 | 0.74 | KCNQ2 (0.52) | KCNQ2JAK2JAK1TYK2JAK3 | |
| SCHEMBL21051214 | 0.74 | KCNQ2 (0.73) | KCNQ2 | |
| SCHEMBL19698503 | 0.72 | KCNQ2 (0.45) | KCNQ2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30487393 | 0.71 | KCNQ2 (0.74) | KCNQ2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676437-B2 | Fluorinated 4-(substituted amino)phenyl carbamate derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190177274-A1 | FLUORINATED 4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10676437-B2 | Fluorinated 4-(substituted amino)phenyl carbamate derivatives | KCNQ2, KCNQ1, KCNN3 | KCNQ2 1/4885JAK2 3707/4885JAK1 4392/4885 |
| US-20190177274-A1 | FLUORINATED 4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNN3 | KCNQ2 1/4885JAK2 3707/4885JAK1 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.