Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734366 | 0.84 | MAPT (0.38) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL22746641 | 0.84 | MAPT (0.38) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL8289269 | 0.78 | KMT2A (0.45) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL14262138 | 0.73 | GABRA1 (0.49) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL21090301 | 0.72 | BCHE (0.42) | MAPTKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL21090302 | 0.72 | BCHE (0.42) | MAPTALDH1A1KDM4EBCHECES1 | |
| SCHEMBL1580661 | 0.71 | TDP1 (0.44) | KMT2AMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL29378510 | 0.71 | TDP1 (0.44) | KMT2AMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL1472980 | 0.71 | ADORA2A (0.52) | MAPTRECQLKMT2AMCL1ALDH1A1 | |
| SCHEMBL11496736 | 0.71 | MAPT (0.47) | MAPTRECQLKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | claimed |
| US-11612877-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-03-28 | — | — | US | claimed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | claimed |
| US-12318756-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2025-06-03 | — | — | US | disclosed |
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | disclosed |
| EP-3720597-B1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES | STICHTING TECHNISCHE WETENSCHAPPEN (NL) | 2023-11-29 | — | — | EP | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-20230201799-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-06-29 | — | — | US | disclosed |
| US-11612877-B2 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-03-28 | — | — | US | disclosed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | disclosed |
| US-20200368721-A1 | Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2020-11-26 | — | — | US | disclosed |
| WO-2019110557-A1 | MACROMOLECULAR COMPOSITIONS COMPRISING INDENE-DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2019-06-13 | — | — | WO | disclosed |