SCHEMBL2109064

SCHEMBL2109064

CC(=O)c1c(C)n(C)n(-c2ccccc2)c1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
ALOX15 P16050 2/20 0.63
MAOA P21397 1/20 0.63
MAOB P27338 1/20 0.63
DPP4 P27487 1/20 0.60
BCHE P06276 1/20 0.58
PTGS2 P35354 1/20 0.58
LMNA P02545 3/20 0.57
GAA P10253 2/20 0.57
ADORA3 P0DMS8 1/20 0.57
KMT2A Q03164 3/20 0.56
MAPT P10636 2/20 0.56
MEN1 O00255 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 3/20 0.56
KDM4E B2RXH2 2/20 0.56
CYP1A2 P05177 2/20 0.55
THRB P10828 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
TP53 P04637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197736 0.88 ALDH1A1 (0.65) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL2047520 0.85 ALDH1A1 (0.61) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL1719195 0.85 KDM4E (0.62) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL22418510 0.85 ALDH1A1 (0.61) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL27899657 0.84 ALDH1A1 (0.56) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL17460926 0.84 L3MBTL1 (0.50) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL198493 0.83 ALDH1A1 (0.58) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL26054746 0.83 ALDH1A1 (0.58) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL28003389 0.83 ALDH1A1 (0.58) ALDH1A1ALOX15MAOAMAOBDPP4
SCHEMBL3874217 0.81 DPP4 (0.66) ALDH1A1ALOX15MAOAMAOBDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
CN-109152363-B Molecules having pesticidal utility, and intermediates, compositions and methods related to these molecules 美国陶氏益农公司 2021-10-15 CN disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 US disclosed
EP-2717860-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI Pharma, LLC (US) 2014-04-16 EP disclosed
US-7905852-B2 Skin-contacting-adhesive free dressing JENNINGS-SPRING BARBARA 2011-03-15 US disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed
US-4260776-A PYRAZOLONE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed