Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400068 | 1.00 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL21993817 | 1.00 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL18950345 | 1.00 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL17145232 | 0.72 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL19400071 | 0.72 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL20650132 | 0.72 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL21036387 | 0.72 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL19537510 | 0.72 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL7626912 | 0.71 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL16053179 | 0.66 | CA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190177327-A1 | SUBSTITUTED METHYL PYRAZOLOPYRIMIDINONE AND METHYL IMIDAZOPYRAZINONE COMPOUNDS AS PDE1 INHIBITORS | DART NEUROSCIENCE LLC (US) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177327-A1 | SUBSTITUTED METHYL PYRAZOLOPYRIMIDINONE AND METHYL IMIDAZOPYRAZINONE COMPOUNDS AS PDE1 INHIBITORS | PDE3A, PDE5A, PDE4A | NOS3 883/4885NOS1 249/4885NOS2 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.