Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 8/20 | 0.45 |
| ▸ | NOS1 | P29475 | 8/20 | 0.45 |
| ▸ | NOS2 | P35228 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19537510 | 1.00 | NOS3 (0.45) | NOS3NOS1NOS2KMT2ACA1 | |
| SCHEMBL21036387 | 1.00 | NOS3 (0.45) | NOS3NOS1NOS2KMT2ACA1 | |
| SCHEMBL19400071 | 1.00 | NOS3 (0.45) | NOS3NOS1NOS2KMT2ACA1 | |
| SCHEMBL20650132 | 1.00 | NOS3 (0.45) | NOS3NOS1NOS2KMT2ACA1 | |
| SCHEMBL18950345 | 0.72 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL19400068 | 0.72 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL21090653 | 0.72 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL21993817 | 0.72 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL22932274 | 0.70 | NOS1 (0.42) | NOS3NOS1NOS2KMT2ACA1 | |
| SCHEMBL7620901 | 0.67 | NOS3 (0.43) | NOS3NOS1NOS2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150572-B2 | Substituted naphthyridine and quinoline compounds as MAO inhibitors | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2015-10-06 | — | — | US | disclosed |